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Palo Alto is a city of about 68,000 people, yet the list of companies that started here or grew up here reads like a history of modern technology. Radio tubes, test instruments, microwave tubes, chips, personal computers, search, online payments, social networks, data software and electric cars all have a Palo Alto chapter. Some of those companies are still here. Many left once they got big.
This section profiles more than 60 of them in detail. Each profile sticks to dates and addresses we could check against company records, government filings, Stanford sources or major news outlets. Where sources disagree or a detail could not be confirmed, we say so or leave it out. For a route that strings the sites together on foot and by bike, use our famous tech addresses tour.
Founded here, based here or passing through
It helps to sort Palo Alto companies into three groups, because "a Palo Alto company" can mean very different things.
- Founded here. Hewlett-Packard, Fairchild Semiconductor, VMware, Palantir and Confinity all started inside city limits. IDEO formed here in 1991 out of a downtown design studio.
- Based here for a long stretch. Varian Associates moved into the first building in the Stanford Industrial Park in 1953. Xerox opened its research center here in 1970. Tesla ran its headquarters from Deer Creek Road for more than a decade.
- Passing through. Google spent a few months downtown in 1999. Facebook spent roughly seven years in Palo Alto before moving to Menlo Park. PayPal left for Mountain View in 2002.
The pattern is consistent. Companies come for Stanford graduates and nearby investors, rent whatever space they can get, then leave when they need a campus. The city itself has limited office space and strict rules on new building heights, so growth usually means moving.
Palo Alto companies at a glance
The table covers the best known names, with the Palo Alto addresses they used and what happened next. Dates refer to Palo Alto activity, not the whole life of the company. A few grew out of Stanford without ever keeping a Palo Alto office we could confirm. Some newer AI companies are based in neighboring cities. The table notes those cases.
| Company | Palo Alto address and era | What happened |
|---|---|---|
| Federal Telegraph Company | Channing Avenue and Emerson Street, founded 1909 | Lee de Forest developed the vacuum tube amplifier and oscillator here from 1911 to 1913. State Landmark No. 836. |
| Hewlett-Packard | 367 Addison Avenue garage from 1938; Page Mill Road from 1940; 1501 Page Mill Road from 1960 | Split in 2015. HP Inc. is still headquartered at 1501 Page Mill Road. Hewlett Packard Enterprise later moved to Texas. |
| Varian Associates | Stanford Industrial Park from 1953 | Split into three companies in 1999. Varian Medical Systems became part of Siemens Healthineers in 2021 and still lists 3100 Hansen Way. |
| Fairchild Semiconductor | 844 East Charleston Road from 1957 | Robert Noyce's integrated circuit, 1959. Alumni founded Intel and many other firms. State Landmark No. 1000. |
| Coherent | Founded May 26, 1966 in Eugene Watson's Palo Alto home; left for Santa Clara in 1992 | Began as Coherent Radiation Laboratories with a carbon dioxide laser. Renamed Coherent, Inc. in 1977. Part of Coherent Corp. since II-VI's 2022 purchase. |
| ALZA | Founded 1968 by Alejandro Zaffaroni; 950 Page Mill Road from 1971 | Known for skin patches and OROS controlled release pills. Bought by Johnson & Johnson in 2001. |
| Xerox PARC | Stanford Research Park from 1970; 3333 Coyote Hill Road | Alto, Ethernet, laser printing and the modern desktop interface. Donated to SRI International in 2023. |
| DNAX Research Institute | Founded 1980 in Palo Alto; last site 901 California Avenue | Immunology lab founded by Zaffaroni with Arthur Kornberg, Paul Berg and Charles Yanofsky. Bought by Schering-Plough in 1982, later Merck Research Laboratories. Palo Alto site closed in 2019. |
| Silicon Graphics | Built on the Geometry Engine chip from Stanford; based in Mountain View from 1981, never in Palo Alto | Renamed SGI in 1999. Assets sold to Rackable Systems in 2009. Its old headquarters now houses the Computer History Museum. |
| Logitech | An early office at 165 University Avenue (years unconfirmed) | Founded in Switzerland in 1981 by Stanford alumni. Headquartered in Lausanne, with a US base in San Jose. |
| Genencor | 925 Page Mill Road; founded 1982 as a Genentech and Corning joint venture | Industrial enzymes for detergents, textiles and grain. Owned in turn by Danisco, DuPont and IFF. The lab still works under the Genencor name. |
| Intuit | Founded in Palo Alto in 1983; first office reported on University Avenue | Quicken came out in 1984. Went public in March 1993. Now headquartered in Mountain View. |
| Cisco | Grew out of Stanford computer rooms; founded December 1984 with no confirmed Palo Alto office | Went public in February 1990. Headquartered at 170 West Tasman Drive, San Jose. |
| CV Therapeutics | 3172 Porter Drive; founded 1990 by Louis G. Lange | Its products were Ranexa and Lexiscan. Bought by Gilead Sciences in 2009 for about $1.4 billion. |
| IDEO | Downtown studios; 100 Forest Avenue was long its headquarters | Formed by merger in 1991. Now headquartered in San Francisco. |
| Incyte | 3160 Porter Drive; founded April 1991 | Sold the LifeSeq gene sequence database. Closed its Palo Alto site in April 2004. Now headquartered in Wilmington, Delaware. |
| Affymetrix | Grew out of the Affymax Research Institute in Palo Alto; spun off in 1993 | Introduced the first GeneChip, an HIV genotyping chip, in 1994. Later based in Santa Clara. Bought by Thermo Fisher Scientific in 2016. |
| Excite | Founded in 1993 by six Stanford students as Architext in Cupertino; no confirmed Palo Alto office | Merged with @Home Network in a deal announced in January 1999. Excite@Home went bankrupt in 2001. |
| Yahoo | A Stanford campus trailer in 1994; no confirmed Palo Alto office | Incorporated in March 1995 with Sequoia Capital backing. Went public in April 1996. Later based in Sunnyvale. |
| Communications & Power Industries | 811 Hansen Way (2004 filing); formed August 11, 1995 from Varian's Electron Devices Business | Klystrons and other microwave tubes. Sold its electron device unit to TransDigm in June 2024. Headquartered in Plano, Texas today. |
| VMware | Founded in Palo Alto in 1998; later 3401 Hillview Avenue | Bought by Broadcom in November 2023. Broadcom moved its headquarters onto the campus. |
| Confinity, X.com and PayPal | 165 University Avenue; 1840 Embarcadero Road by 2001 | Moved headquarters to Mountain View in 2002. Bought by eBay in 2002, spun off in 2015. |
| 165 University Avenue, February to mid 1999 | Moved to Mountain View later in 1999. | |
| Palantir | Downtown Palo Alto, 2003 to 2020 | Headquarters moved to Denver in 2020 and to the Miami area in 2026. Still keeps a Palo Alto office. |
| Jazz Pharmaceuticals | Founded in Palo Alto in March 2003; US address 3170 Porter Drive | Started by former ALZA executives. Headquartered in Dublin, Ireland since the 2012 Azur merger. Known for Xyrem, Xywav and Epidiolex. |
| 471 Emerson Street from 2005; 1601 California Avenue from 2009 | Began moving to Menlo Park in 2011. Now Meta. | |
| Bill.com | 1810 Embarcadero Road (2019 filing); formed in 2006 as Cashboard | Went public in December 2019. Now BILL Holdings, headquartered in San Jose. |
| Uniphore | US address 1001 Page Mill Road, Building 2 | Founded in 2008 at IIT Madras. Enterprise AI company that reported a $260 million Series F in October 2025. |
| C3 AI | Founded 2009 by Thomas M. Siebel; headquarters 1400 Seaport Blvd., Redwood City | AI software for large companies and governments. Went public on the New York Stock Exchange on December 9, 2020. |
| Tesla | 3500 Deer Creek Road from 2010; 3000 Hanover Street from 2023 | Corporate headquarters moved to Austin in 2021. Engineering headquarters stayed in Palo Alto. |
| Udacity | Grew from Stanford's free AI course in fall 2011; no confirmed Palo Alto office | Founded by Sebastian Thrun, David Stavens and Mike Sokolsky. Bought by Accenture in May 2024. |
| Coursera | Grew from Stanford's free online courses of 2011; based in Mountain View | Founded in 2012 by Andrew Ng and Daphne Koller. Went public in March 2021. Combined with Udemy in May 2026. |
| 1X Technologies | Founded 2014 in Norway as Halodi Robotics; now headquartered in Palo Alto (no street published) | Builds NEO, a humanoid robot for the home. Opened a factory in Hayward in 2026. |
| Toyota Research Institute | Started 2016; headquarters 4440 El Camino Real, Los Altos | Toyota subsidiary researching AI, automated driving, robotics and materials. Led by Gill Pratt. |
| Nuro | Founded September 2016; headquarters 1290 Terra Bella Avenue, Mountain View | Built small delivery robots, then switched to licensing its Nuro Driver software. Reported a $203 million Series E in 2025. |
| Character.AI | Founded November 2021 by two former Google engineers; office in Redwood City | Chatbots people talk to as characters. Licensed its technology to Google. Announced a Chapter 11 sale process on October 13, 2026. |
| Broadcom | 3421 Hillview Avenue (former VMware campus) from November 2023 | Moved its headquarters from San Jose after buying VMware. |
| Hippocratic AI | Founded 2023; Palo Alto datelines, no street published | AI agents that talk with patients by phone. Reported a $126 million Series C in November 2025. |
| Pika | 849 High Street (2026 terms of service); founded 2023 | AI video generator started by former Stanford Ph.D. students Demi Guo and Chenlin Meng. |
| Safe Superintelligence (SSI) | Offices in Palo Alto and Tel Aviv; announced June 19, 2024 | Research lab cofounded by Ilya Sutskever, Daniel Gross and Daniel Levy. No products released. |
The instrument and microwave era
Palo Alto's first technology firms made hardware for engineers. The Federal Telegraph Company, founded in 1909 by Stanford graduate Cyril Elwell, built radio equipment near what is now Channing Avenue and Emerson Street. A sidewalk plaque marks the spot.
Three decades later, Bill Hewlett and Dave Packard built audio oscillators in a garage a few blocks away. Their company grew into one of the largest technology firms in the world and anchored Palo Alto for more than 80 years. The Hewlett-Packard profile follows it from the garage to the 2015 split. The garage itself has its own page under attractions.
Varian Associates came out of the same Stanford circle. The Varian brothers had built the klystron, a microwave tube, at Stanford in 1937. Their company moved into the new industrial park on university land in 1953 and stayed for decades.
The research park era
Stanford could not sell its land, but it could lease it. In 1951 the university and the city created the Stanford Industrial Park, now called Stanford Research Park, along Page Mill Road. Varian, HP, Xerox, Lockheed and later Facebook, VMware and Tesla all leased space there. Our guide to Stanford Research Park explains how the ground leases work.
Xerox's Palo Alto Research Center, opened in 1970, is the most famous research park tenant. Its researchers built the Alto computer, Ethernet and laser printing. Xerox made money from the printers but left most of the computer ideas for others to sell. The Xerox PARC profile covers that story and the 2023 handover to SRI International.
The downtown internet era
In the late 1990s the action shifted to downtown Palo Alto. Small companies rented space above shops on University Avenue and its side streets. One building, 165 University Avenue, became famous because so many of its tenants made it big. Google moved in with eight employees in February 1999. Confinity, the startup that launched PayPal, used it as its second office. Logitech and the phone maker Danger also worked there.
Facebook arrived in 2004 and became the defining downtown company of the next decade. By 2009 it had spread across about ten downtown buildings before consolidating in Stanford Research Park. Palantir grew up downtown during the same years.

Big campuses and big departures
The 2010s brought the largest single company footprints the city had seen since HP's peak. VMware built a campus on Hillview Avenue. Tesla took a former HP and Agilent manufacturing complex on Deer Creek Road for its headquarters and powertrain work.
Then came a string of headline departures. Hewlett Packard Enterprise announced in 2017 that it would leave Palo Alto. Palantir moved its headquarters to Denver in August 2020. Tesla announced in December 2021 that its headquarters had moved to Austin, Texas. Each move made news, but in practice none of these companies left the region entirely. Tesla even came back in 2023 with a global engineering headquarters on Hanover Street. The Tesla profile has the details.
Who is here now
As of late 2026, the largest corporate headquarters in the city are HP Inc. on Page Mill Road and Broadcom on Hillview Avenue. Tesla's engineering headquarters, SAP's research park campus and Varian Medical Systems, now part of Siemens Healthineers, add thousands more jobs. Newer arrivals in Stanford Research Park include robotics and AI companies. General Motors leased about 340,000 square feet at 3411 Hillview Avenue in 2026.
Downtown still works as a first office for young companies. Turnover is high, so the names change every few years. Our startups hub covers today's ecosystem, accelerators and jobs.
Good to know
- Nearly every address on this page is a private office or home. Look from the sidewalk and do not enter lobbies, parking garages or yards.
- The HP Garage plaque, the Federal Telegraph sidewalk plaque and the Facebook marker at 471 Emerson Street are the only company sites with markers you can read from the street.
- Stanford Research Park is spread out. A bike or car makes it far easier to see Page Mill Road, Hanover Street, Hillview Avenue and Coyote Hill Road in one trip.
- Visiting for meetings? Compare hotels near Stanford Research Park and downtown before big Stanford weekends push rates up.
How we checked these histories
Company histories get retold so often that small errors spread. We relied first on primary records: company press releases and history pages, SEC filings that list headquarters addresses, Stanford sources and state landmark listings. We then checked dates against major news coverage from the time. Some popular claims did not survive that check, so they are not here. When a profile says a detail is reported rather than confirmed, that is deliberate.
Addresses also change meaning over time. Stanford Research Park buildings are often renumbered, split or rebuilt. A building that housed one company in 1995 may hold three different tenants today. Each profile notes what is at the address now when we could confirm it.
In this section
Frequently asked questions
What famous companies were founded in Palo Alto?
Hewlett-Packard began in a garage at 367 Addison Avenue in 1939. Fairchild Semiconductor, VMware, Palantir, Confinity (the company that launched PayPal) and the design firm IDEO also started in Palo Alto. Google and Facebook were founded elsewhere but spent important early years here.
Which big companies are headquartered in Palo Alto today?
HP Inc. is headquartered at 1501 Page Mill Road and Broadcom at 3421 Hillview Avenue on the former VMware campus. Tesla keeps its global engineering headquarters at 3000 Hanover Street, though its corporate headquarters moved to Austin in 2021.
Why did so many companies leave Palo Alto?
Most simply outgrew it. Downtown offices are small and Stanford Research Park leases are limited, so fast growing firms moved to bigger campuses in Mountain View, Menlo Park or San Jose. A few, like Tesla and Palantir, also moved their headquarters out of California.
Can I visit these company sites?
You can see most of them from public sidewalks and streets, but nearly all are private offices with no public access. The HP Garage and the Facebook office marker at 471 Emerson Street are the easiest stops for visitors.
What is the lucky building in Palo Alto?
It is 165 University Avenue downtown. Google, Confinity (PayPal's predecessor), Logitech and Danger all used it early on, which earned it the nickname.